Figure 2
From: Benign esophageal stricture model construction and mechanism exploration

Pathological progress of esophageal stricture in rats. (A) The rats in the acute inflammatory phase (Day 1). Regenerated epithelium was disrupted, and the hyperemia and edema occurred in submucosa layer. (B) The rats in the proliferation phase (Day 7 in model group). The extensive granulation tissue formation. (C) The rats in the anaphase of proliferation (Day 10 in model group). Fibroblasts proliferated, new capillaries increased, and regenerated epithelium was repaired. (D) The rats in the plastic remodeling phase (Day 14 in model group). Abundant fibrous connective tissue appeared. (E) The epithelial layer underwent gradual repair. (F) The inflammatory area gradually decreased.