Figure 3

An individualized predictive model of OS in glioma patients. (A) NFAT1 expression and IL6/JAK/STAT signaling pathway were significantly correlated in CGGA database. (B) Seven most representative genes of IL6/JAK/STAT signaling pathway were screened by LASSO-COX analysis. (C) Nomogram accurately predicts the OS at 1, 2, 3, 5 and 10 years after surgery in glioma patients. (D) As part of the individualized prediction model, the C index was used to evaluate the prediction effect of risk score and various clinical prognostic factors on OS. (E,F) Calibration plots show predicted and actual OS comparisons about 1, 2, 3, 5 and 10 years about the training and validation groups.