Figure 1

Representative images of retinal microvasculature measured using OCTA. (a–c) SFAZ area and (d–f) DFAZ area; the dark avascular area in both the SCP and DCP was manually measured using the IMAGEnet program by outlining its boundary. (g–i) SCPD and (j–l) DCPD; vessel density in the SCP and DCP layers were automatically calculated using IMAGEnet. The central number was recorded as either foveal SCPD or DCPD. The parafovea was segmented into four regions, namely top, bottom, temporal, and nasal, and the mean vessel density of each region was computed and noted as parafoveal SCPD and DCPD (a, d, g, j: patch occlusion group; b, e, h, k: optical correction group; c, f, i, l: control group). The images were created using the built-in software program IMAGEnet6 (version 1.25.16650; Topcon, URL: https://topconhealthcare.jp/products/imagenet-6/) in the DRI OCT Triton Plus instrument (Topcon Co., Tokyo, Japan). OCTA, optical coherence tomography angiography; SFAZ, superficial retinal capillary plexus foveal avascular zone; DFAZ, deep retinal capillary plexus foveal avascular zone; SCPD, vessel density of the superficial retinal capillary plexus; DCPD, vessel density of the deep retinal capillary plexus.