Table 5 Genera with the most contribution on model predictions according to SHAP analysis for each cancer type (in descending order of contribution). Corresponding SHAP scores are provided for each feature.

From: Machine learning-based approaches for cancer prediction using microbiome data

 

Overall

 

Correct predictions

 

Incorrect predictions

 

COAD

Porphyromonas

(0.099)

Porphyromonas

(0.216)

Porphyromonas

(2.005)

Granulicatella

(0.031)

Akkermansia

(0.033)

Akkermansia

(0.289)

Bacteroides

(0.025)

Granulicatella

(0.031)

Barnesiella

(0.202)

Solobacterium

(0.021)

Streptococcus

(0.029)

Parabacteroides

(0.115)

Fusobacterium

(0.020)

Alistipes

(0.024)

Ruminococcus

(0.072)

READ

Porphyromonas

(0.294)

Porphyromonas

(0.965)

Porphyromonas

(0.209)

Granulicatella

(0.117)

Granulicatella

(0.293)

Parvimonas

(0.156)

Streptococcus

(0.070)

Streptococcus

(0.139)

Bacteroides

(0.035)

Solobacterium

(0.042)

Solobacterium

(0.131)

Akkermansia

(0.022)

Parabacteroides

(0.031)

Campylobacter

(0.111)

Sutterella

(0.022)

HNSC

Helicobacter

(0.236)

Helicobacter

(0.230)

Leptotrichia

(0.020)

Lactobacillus

(0.044)

Lactobacillus

(0.040)

Alloprevotella

(0.011)

Fusobacterium

(0.011)

Fusobacterium

(0.013)

Acinetobacter

(0.009)

Leptotrichia

(0.006)

Alloprevotella

(0.005)

Prevotella

(0.008)

Alloprevotella

(0.005)

Clostridium

(0.005)

Abiotrophia

(0.008)

STAD

Helicobacter

(0.336)

Helicobacter

(0.433)

Helicobacter

(0.072)

Lactobacillus

(0.042)

Capnocytophaga

(0.019)

Prevotella

(0.020)

Veillonella

(0.017)

Lactobacillus

(0.013)

Clostridium

(0.013)

Fusobacterium

(0.012)

Clostridium

(0.009)

Capnocytophaga

(0.012)

Prevotella

(0.012)

Fusobacterium

(0.009)

Actinomyces

(0.009)

ESCA

Helicobacter

(0.131)

Helicobacter

(0.203)

Lactobacillus

(0.066)

Streptococcus

(0.042)

Lactobacillus

(0.097)

Streptococcus

(0.055)

Prevotella

(0.031)

Acinetobacter

(0.034)

Prevotella

(0.038)

Lactobacillus

(0.030)

Capnocytophaga

(0.018)

Atopobium

(0.026)

Aloprevotella

(0.022)

Prevotella

(0.009)

Abiotrophia

(0.011)