Figure 4

ACEI blunted the exacerbated lung damage by irradiation in DCS. The BALF Ang II level after irradiation plus decompression injury with or without enalapril treatment (A). The overall mortality (B) and survival curve in each group (C). Representative images of lung tissue sections (D) and the Lung injury score (E) in each group. The mRNA levels of IL-1β (F), IL-6 (G), and TNF-α (H) in each group. The levels of IL-1β (I), IL-6 (J), and TNF-α (K) in BALF after irradiation plus decompression injury with or without enalapril treatment. Values are mean ± SE; n = 5 in each group of (A), (F), (G), (H), (I), (J), and (K); n = 20 in each group of (B) and (C); n = 6 in each group of (D) and (E). *P < 0.05, **P < 0.01; ***P < 0.001; ****P < 0.0001.