Figure 4 | Scientific Reports

Figure 4

From: Activation of SARS-CoV-2 by trypsin-like proteases in the clinical specimens of patients with COVID-19

Figure 4

Effect of anaerobic oral bacterial culture supernatant on the infectivity of SARS-CoV-2 using clinical specimens. After adding the five clinical specimens (A–E) containing the SARS-CoV-2 delta variant to the cells, the increase in infectivity of viruses was calculated after treatment with culture supernatants of (A) Prevotella melaninogenica, (B) Prevotella intermedia, and (C) Fusobacterium necrophorum based on the infectivity of the virus treated in the control medium. The results shown are from three independent assays, with error bars representing standard deviations. Significance was determined by the Student’s t-test in comparison to the data of no treatment (Ctrl): *P < 0.05; **P < 0.01.

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