Figure 4 | Scientific Reports

Figure 4

From: Correlation between biological and mechanical properties of extracellular matrix from colorectal peritoneal metastases in human tissues

Figure 4

(A) YM values (mean median value ± std of the mean) of healthy ECMs of the 13 patients affected by adenocarcinoma versus their age (circles and crosses represent men and females, respectively). (B) YM values as in (A) for patients who did not (−) and did (+) undergo chemotherapy. (C–H) Relative stiffening of the neoplastic ECMs from the same patients, versus: (C) chemotherapic treatment; (D) the patients’ age; (E) the presence of protein activating mutations in KRAS and BRAF genes; (F) the patients’ sex; (G) histology—MA mucinous adenocarcinoma, AS adenocarcinoma of the sigma, A adenocarcinoma, H tumour grade.

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