Figure 1 | Scientific Reports

Figure 1

From: Molecular characteristics and therapeutic implications of Toll-like receptor signaling pathway in melanoma

Figure 1

Pan-cancer analysis of TLR-associated genes. (A) Data on CNV amplification and loss frequency of TLR-associated genes in different cancer types. The colors of the lines indicate different cancers, and the lengths of the lines indicate the degree of CNV in the genes involved. (B) The mRNA expression of TLR-related genes in tumors and adjacent normal tissues was compared, and the red to green circles indicated the expression level from high to low, and the circle size indicated statistical significance. (C) SNV frequency data for TLR-related genes in different cancer types, and the numbers indicate the frequency of mutations. (D) The degree of methylation of TLR-related genes in various cancers, with the circle color from red to green indicating the degree of methylation of tumor tissue relative to normal tissue, and the circle size indicating statistical significance. (E) TLR-related genes are associated with prognosis in various types of cancer, with red and green representing risk genes and protective genes, respectively, and gray indicating non-statistically significant.

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