Table 3 Clinical characteristics of the pregnancy-optic neuritis group and the pregnancy-control group.

From: Pregnancy prevalence and outcomes after optic neuritis in South Korea

 

Pregnancy-ON group (N = 550)

Pregnancy-control group (N = 1650)

P-value

SMD

Age of pregnancy (Mean ± SD)

31.34 ± 5.38

31.34 ± 5.38

1.0000

0

Multiple sclerosis (N, %)

1

0.18

0

0

0.2500*

0.060

Neuromyelitis optica (N, %)

2

0.36

0

0

0.0624*

0.085

Autoimmune dieases (N, %)

 Bechet or Sjorgen syndrome

0

0

1

0.06

1.0000*

0.035

 Autoimmune thyroiditis

2

0.36

0

0

0.0624*

0.085

 Rheumatic arthritis

1

0.18

0

0

0.2500*

0.060

Cancer (N, %)

1

0.18

4

0.24

1.0000*

0.013

Diabetes mellitus (N, %)

6

1.09

22

1.33

0.6605

0.022

Hypertension (N, %)

3

0.55

9

0.55

1.0000*

0.000

Dyslipidemia (N, %)

18

3.27

58

3.52

0.7875

0.013

Alcohol addiction (N, %)

0

0

2

0.12

1.0000*

0.049

Thyroid disease (N, %)

26

4.73

58

3.52

0.1989

0.061

Obesity (N, %)

0

0

4

0.24

0.5777*

0.070

Ovarian dysfunction (N, %)

10

1.82

26

1.58

0.6980

0.019

Entometriosis (N, %)

3

0.55

17

1.03

0.2995

0.055

Pre-eclampsia (N, %)

12

2.18

5

0.3

 < 0.0001*

0.17

Eclampsia (N, %)

0

0

1

0.06

1.0000*

0.035

Gestational hypertension (N, %)

5

0.91

7

0.42

0.1884*

0.06

Diabetes mellitus in pregnancy (N, %)

107

19.45

249

15.09

0.0161

0.116

Placenta previa (N, %)

3

0.55

14

0.85

0.5862*

0.036

Premature separation of placenta (N, %)

1

0.18

4

0.24

1.0000*

0.013

Preterm delivery (N, %)

62

11.27

56

3.39

 < 0.0001

0.306

Pregnancy or postpartum infection (N, %)

111

20.18

232

14.06

0.0006

0.163

Delayed fetal growth (N, %)

1

0.18

0

0

0.2500*

0.064

C-sec (N, %)

128

23.27

197

11.94

 < 0.0001

0.301

  1. P-values shown in bold indicate statistically significant differences between the two groups.
  2. ON optic neuritis, SMD standardized mean difference, C-sec cesarean section.
  3. *P-values by Fisher’s exact test, other p-values were anlyazed by Chi-squared test.