Table 3 Clinical characteristics of the pregnancy-optic neuritis group and the pregnancy-control group.
From: Pregnancy prevalence and outcomes after optic neuritis in South Korea
Pregnancy-ON group (N = 550) | Pregnancy-control group (N = 1650) | P-value | SMD | |||
|---|---|---|---|---|---|---|
Age of pregnancy (Mean ± SD) | 31.34 ± 5.38 | 31.34 ± 5.38 | 1.0000 | 0 | ||
Multiple sclerosis (N, %) | 1 | 0.18 | 0 | 0 | 0.2500* | 0.060 |
Neuromyelitis optica (N, %) | 2 | 0.36 | 0 | 0 | 0.0624* | 0.085 |
Autoimmune dieases (N, %) | ||||||
Bechet or Sjorgen syndrome | 0 | 0 | 1 | 0.06 | 1.0000* | 0.035 |
Autoimmune thyroiditis | 2 | 0.36 | 0 | 0 | 0.0624* | 0.085 |
Rheumatic arthritis | 1 | 0.18 | 0 | 0 | 0.2500* | 0.060 |
Cancer (N, %) | 1 | 0.18 | 4 | 0.24 | 1.0000* | 0.013 |
Diabetes mellitus (N, %) | 6 | 1.09 | 22 | 1.33 | 0.6605 | 0.022 |
Hypertension (N, %) | 3 | 0.55 | 9 | 0.55 | 1.0000* | 0.000 |
Dyslipidemia (N, %) | 18 | 3.27 | 58 | 3.52 | 0.7875 | 0.013 |
Alcohol addiction (N, %) | 0 | 0 | 2 | 0.12 | 1.0000* | 0.049 |
Thyroid disease (N, %) | 26 | 4.73 | 58 | 3.52 | 0.1989 | 0.061 |
Obesity (N, %) | 0 | 0 | 4 | 0.24 | 0.5777* | 0.070 |
Ovarian dysfunction (N, %) | 10 | 1.82 | 26 | 1.58 | 0.6980 | 0.019 |
Entometriosis (N, %) | 3 | 0.55 | 17 | 1.03 | 0.2995 | 0.055 |
Pre-eclampsia (N, %) | 12 | 2.18 | 5 | 0.3 | < 0.0001* | 0.17 |
Eclampsia (N, %) | 0 | 0 | 1 | 0.06 | 1.0000* | 0.035 |
Gestational hypertension (N, %) | 5 | 0.91 | 7 | 0.42 | 0.1884* | 0.06 |
Diabetes mellitus in pregnancy (N, %) | 107 | 19.45 | 249 | 15.09 | 0.0161 | 0.116 |
Placenta previa (N, %) | 3 | 0.55 | 14 | 0.85 | 0.5862* | 0.036 |
Premature separation of placenta (N, %) | 1 | 0.18 | 4 | 0.24 | 1.0000* | 0.013 |
Preterm delivery (N, %) | 62 | 11.27 | 56 | 3.39 | < 0.0001 | 0.306 |
Pregnancy or postpartum infection (N, %) | 111 | 20.18 | 232 | 14.06 | 0.0006 | 0.163 |
Delayed fetal growth (N, %) | 1 | 0.18 | 0 | 0 | 0.2500* | 0.064 |
C-sec (N, %) | 128 | 23.27 | 197 | 11.94 | < 0.0001 | 0.301 |