Figure 1 | Scientific Reports

Figure 1

From: Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats

Figure 1

G2-SUISO attenuated CDHCFF-induced nonalcoholic steatohepatitis. (A) The experimental design and timeline of the groups was shown. (B) The liver weight-to-body weight ratio in the five groups is shown. (C) G2-SUISO treatment significantly reduced serum ALT, AST and TC levels in NASH rats. (D) Hematoxylin and eosin (HE) staining of liver specimens in different groups suggested that G2-SUISO improved hepatic steatosis in NAFLD rats. The yellow triangle represents the area of inflammatory cell infiltration. White vacuoles showed lipids (yellow arrow) in HE staining (magnification × 100 & × 200). (E) An analysis of the HE staining of fatty liver specimens is shown. Each bar represents the mean ± SD. (F) Liver sections of five groups were stained by Oil Red O solution. Red areas showed lipids in Oil Red O staining (magnification × 100 & × 200). (G) An analysis of the Oil Red O staining of fatty liver specimens is shown. Each bar represents the mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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