Table 2 CYP2B6 and CYP2C19 allele and genotype frequencies, and genotype based phenotypes of neuroblastoma patients (N = 50).

CYP genotype based phenotype estimation

 CYP2B6 alleles

  *4

5

5.0

2.2–6.2

  *5

11

11.0

9–12.2

  *6

22

22.0

7–28.1

  *9

0

0

0–4.4

  *22

1

1.0

1.4–2.4

Poor/intermediate CYP2B6 metabolizer (N = 20)

 CYP2B6 genotypes

  *1/*6

14

28.0

22.1–22.9

  *6/*6

2

4.0

5.4–7.3

  *5/*6

2

4.0

5.3–7.3

  *4/*6

2

4.0

 < 2.1

Normal/rapid CYP2B6 metabolizer (N = 30)

 *1/*1

17

34.0

21–24.1

 *1/*5

9

18.0

7.3–11.3

 *1/*4

3

6.0

1–4

 *1/*22

1

2.0

1.3–2.1

 CYP2C19 alleles^c

  *2

15

15.3

6.0–15.0

  *3

0

0

 < 1

  *4

0

0

 < 1

  *17

20

20.4

21.5–25.0

Poor/intermediate CYP2C19 metabolizer (N = 12)

 CYP2C19 genotypes^c

  *1/*2

6

12.2

18.3–18.5

  *2/*2

3

6.1

2.1

  *2/*17

3

6.1

6.3

Normal CYP2C19 metabolizer (N = 23)

 *1/*1

23

46.9

39.0–40.5

Rapid/ultrarapid CYP2C19 metabolizer (N = 14)

 *1/*17

11

22.4

26.9–27.5

 *17/*17

3

6.1

4.6–4.7