Table 3 The top 10 differently expressed circRNAs involved in LPS-induced autophagy.
From: Identification of autophagy-associated circRNAs in sepsis-induced cardiomyopathy of mice
circRNA | Fold change | Regulation | miRNA | Target gene | Downstream pathways or biological proecsses |
|---|---|---|---|---|---|
circRNA.27393 | 21.24 | Up | mmu-miR-1933-3p | Dap | Autophagy |
mmu-miR-448-5p | Rnf152 | Autophagy mTOR signaling pathway | |||
mmu-miR-125a-5p | Ajuba | Hippo signaling pathway | |||
mmu-miR-125b-5p | Ajuba | Hippo signaling pathway | |||
circRNA.27392 | 12.80 | Up | mmu-miR-1903 | Vav3 | cAMP signaling pathway |
mmu-miR-669f.-5p | Bcl2 | Autophagy PI3K-Akt signaling pathway HIF-1 signaling pathway | |||
mmu-miR-770-3p | Thbs1 | PI3K-Akt signaling pathway | |||
mmu-miR-671-5p | Arrb1 | MAPK signaling pathway | |||
mmu-miR-705 | Laptm5 | Lysosome | |||
circRNA.5564 | 10.77 | Up | mmu-miR-105 | Hspa1b | MAPK signaling pathway |
mmu-miR-5114 | Gli2 | Hippo signaling pathway | |||
mmu-miR-1933-3p | Dap | Autophagy | |||
mmu-miR-770-5p | Rnf152 | Autophagy mTOR signaling pathway | |||
circRNA.5562 | 9.53 | Up | mmu-miR-3100-5p | Bmp2 | Hippo signaling pathway |
mmu_circ_0005739 | 9.07 | Up | mmu-miR-1897-5p | Map3k12 | MAPK signaling pathway |
mmu-miR-3091-5p | Mef2c | MAPK signaling pathway | |||
mmu-miR-345-3p | Adrb2 | cAMP signaling pathway Calcium signaling pathway | |||
circRNA.5566 | 8.71 | Up | mmu-miR-1953 | Bmp2 | Hippo signaling pathway |
mmu-miR-5114 | Gli2 | Hippo signaling pathway | |||
mmu-miR-3100-5p | Bmp2 | Hippo signaling pathway | |||
mmu-miR-721 | Map3k12 | MAPK signaling pathway | |||
mmu-miR-1933-3p | Dap | Autophagy | |||
circRNA.5563 | 8.47 | Up | mmu-miR-105 | Hspa1b | MAPK signaling pathway |
mmu-miR-5130 | Orai2 | Calcium signaling pathway | |||
mmu-miR-711 | Slc7a5 | mTOR signaling pathway | |||
circRNA.27348 | 8.18 | Up | mmu-miR-763 | Tead3 | Hippo signaling pathway |
mmu-miR-3104-5p | Fzd7 | mTOR signaling pathway Hippo signaling pathway | |||
circRNA.5573 | 7.95 | Up | mmu-miR-1198-5p | Nr4a1 | PI3K-Akt signaling pathway MAPK signaling pathway |
mmu-miR-1896 | Bmp2 | Hippo signaling pathway | |||
mmu-miR-1941-5p | Fzd7 | mTOR signaling pathway Hippo signaling pathway | |||
mmu-miR-1954 | Il1r1 | MAPK signaling pathway | |||
circRNA.27394 | 7.14 | Up | mmu-miR-1904 | Bnip3 | autophagy |
mmu-miR-693-3p | Fgf11 | PI3K-Akt signaling pathway MAPK signaling pathway | |||
mmu-miR-3097-3p | Ddit4 | PI3K-Akt signaling pathway mTOR signaling pathway | |||
mmu-miR-199a-5p | Serpine1 | HIF-1 signaling pathway Hippo signaling pathway | |||
mmu-miR-345-3p | Adrb2 | cAMP signaling pathway Calcium signaling pathway |
