Table 1 Comparison of baseline characteristics and transplantation-related outcome of liver transplantation recipients between first transplantation group and retransplantation group.
First transplantation (n = 2134) | Retransplantation (n = 103) | P-value | ||
|---|---|---|---|---|
Recipient-related variable | Recipient sex (male vs. female) | 1577/557 (73.9%) | 71/32 (68.9%) | 0.232 |
Recipient age (years) | 47.2 ± 17.7 | 44.0 ± 18.6 | 0.060 | |
Hypertension | 274 (12.8%) | 8 (7.8%) | 0.130 | |
Diabetes mellitus | 458 (21.5%) | 27 (26.2%) | 0.253 | |
Etiology (Hepatitis B virus vs. others) | 0.010 | |||
Hepatitis B virus | 1414 (66.7%) | 56 (54.4%) | ||
Hepatitis C virus | 97 (4.6%) | 5 (4.9%) | ||
Alcohol | 321 (15.1%) | 12 (11.7%) | ||
Others | 289 (13.6%) | 30 (29.1%) | ||
Hepatocellular carcinoma | 1108 (52.3%) | 37 (36.3%) | 0.002 | |
Pre-transplant albumin | 3.2 ± 0.9 | 3.1 ± 0.4 | 0.008 | |
Pre-transplant total bilirubin | 10.9 ± 14.0 | 22.3 ± 15.2 | < 0.001 | |
Pre-transplant prothrombin time, INR | 2.05 ± 2.00 | 2.51 ± 1.55 | 0.002 | |
Pre-transplant creatinine | 1.3 ± 1.2 | 2.1 ± 1.8 | 0.001 | |
Hepatic encephalopathy | 501 (23.5%) | 22 (21.4%) | 0.620 | |
Variceal bleeding | 347 (16.3%) | 5 (4.9%) | 0.001 | |
Ascites | 1269 (59.5%) | 44 (42.7%) | 0.001 | |
Hepatorenal syndrome | 271 (12.7%) | 50 (48.5%) | < 0.001 | |
Spontaneous bacterial peritonitis | 204 (9.6%) | 6 (5.8%) | 0.204 | |
Pretransplant ventilator care | 94 (4.4%) | 22 (21.4%) | < 0.001 | |
MELD score | 20.3 ± 11.6 | 32.1 ± 8.8 | < 0.001 | |
CTP score | 9.1 ± 2.7 | 10.3 ± 2.0 | < 0.001 | |
Donor-related variable | Type of transplantation | < 0.001 | ||
Living donor | 1636 (76.7%) | 12 (11.7%) | ||
Deceased donor | 498 (23.3%) | 91 (88.3%) | ||
Donor sex (male vs. female) | 1374/760 (64.4%) | 64/39 (62.1%) | 0.642 | |
Donor age (years) | 36.0 ± 14.1 | 46.0 ± 15.2 | < 0.001 | |
ABO incompatibility | 224 (10.5%) | 2 (1.9%) | 0.002 | |
Graft weight | 849 ± 343 | 1316 ± 375 | < 0.001 | |
Graft-recipient weight ratio | 1.28 ± 0.55 | 2.11 ± 0.67 | < 0.001 | |
Warm ischemic time | 40.2 ± 26.2 | 35.0 ± 15.1 | 0.066 | |
Cold ischemic time | 134 ± 114 | 287 ± 158 | < 0.001 | |
Graft type (whole vs. partial) | < 0.001 | |||
Whole liver | 475 (22.5%) | 88 (86.3%) | ||
Right liver | 1595 (75.7%) | 14 (13.7%) | ||
Left liver | 36 (1.7%) | – | ||
Right posterior | 1 (0.0%) | – | ||
Recipient outcome | 30-day complication | 1079 (50.6%) | 82 (80.6%) | < 0.001 |
None | 1050 (49.2%) | 20 (19.4%) | < 0.001 | |
Grade I/II | 315 (14.8%) | 14 (13.6%) | ||
Grade III | 610 (28.6%) | 35 (34.0%) | ||
Grade IV/V | 159 (7.5%) | 34 (33.0%) | ||
Primary graft failure | 184 (8.6%) | 34 (33.0%) | < 0.001 | |
Secondary graft failure | 596 (27.9%) | 60 (58.3%) | < 0.001 | |
Death | 541 (25.6%) | 55 (53.4%) | < 0.001 |
