Table1 Preoperative clinical and biochemical characteristics of all patients (training + validation group).
From: Predictive model for persistent hypertension after surgical intervention of primary aldosteronism
Characteristics | Total | Persistent hypertension(n = 163) | Normal blood pressure(n = 190) | P |
|---|---|---|---|---|
Age, y | 44.0 (38.0–55.0) | 43.0 (43.0–55.5) | 45.0 (35.0–54.8) | 0.001 |
Sex, M/F | 142/211 (38.1%) | 85/78 (52.1%) | 57/133 (30.0%) | < 0.001 |
SBP, mmHg | 180 (170–200) | 184 (175–200) | 180 (166–190) | < 0.001 |
DBP, mmHg | 110 (100–120) | 110 (100–120) | 110 (100–120) | 0.011 |
BMI ≥ 25, yes/no | 131/222 (37.1%) | 80/83 (49.1%) | 51/139 (26.8%) | < 0.001 |
Duration of HT, y | 5.0 (1.0–10.0) | 8.0 (3.0–10.0) | 3.0 (0.81–7.0) | < 0.001 |
Family history of HT, yes/no | 121/232 (34.3%) | 63/100 (38.7%) | 58/132 (30.5%) | 0.136 |
Diabetes, yes/no | 55/298 (21.8%) | 44/119 (27.0%) | 11/179 (5.8%) | < 0.001 |
HHD, yes/no | 88/265 (24.9%) | 56/107 (34.4%) | 32/158 (16.8%) | < 0.001 |
RH, yes/no | 109/244 (30.9%) | 65/98 (39.9%) | 44/146 (23.2%) | 0.001 |
DDD of antihypertensive medication | 3.6 (2.6–4.4) | 3.6 (2.6–4.4) | 3.0 (2.5–4.0) | 0.003 |
ARR, pg·mL-1/uIU·mL-1 | 340 (135–618) | 270 (110–541) | 404 (154–674) | 0.002 |
PAC, pg/mL | 326 (214–503) | 293 (192–459) | 351 (255–533) | 0.006 |
DRC, uIU/mL | 0.96 (0.50–2.10) | 1.09 (0.50–2.34) | 0.79 (0.50–1.79) | 0.045 |
Lowest serum K+, mmol/L | 2.68 (2.20–300) | 2.70 (2.40–3.00) | 2.60 (2.16–2.90) | 0.016 |
eGFR, (mL/min/1.73m2) | 101.2 (82.9–114.4) | 96.0 (75.6–109.2) | 107.2 (91.3–119.5) | < 0.001 |
TC, mmol/L | 4.03 ± 0.83 | 4.08 ± 0.90 | 3.99 ± 0.76 | 0.297 |
TG, mmol/L | 1.15 (0.80–1.63) | 1.33 (0.98–1.89) | 0.98 (0.73–1.40) | < 0.001 |
Diameter of nodules, cm | 1.5 (1.0–2.0) | 1.4 (1.0–1.7) | 1.5 (1.0–2.0) | 0.017 |
Surgical side, L/R | 208/145 (58.9%) | 98/65 (60.1%) | 110/80 (57.9%) | 0.752 |
Total adrenalectomy, yes/no | 204/149 (52.0%) | 97/66 (59.5%) | 107/83 (56.3%) | 0.619 |
