Figure 6 | Scientific Reports

Figure 6

From: Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct

Figure 6

p300 IDRs are dispensable for condensate formation. (a) Disorder prediction of p300 IDRs as shown via IUPRED2 analysis. (b) Schematics of BRD4-p300 (FL), (IDR) and (ΔIDR) constructs; different domains and disordered regions are indicated. (c) Micrographs of all the BRD4-p300 constructs from (a); scale bars = 10 µm. Constructs marked with an asterisk were expressed via transient transfection. (d) Quantification of the micrographs represented in (c), expressed in stable cell lines. (e) Quantification of the micrographs represented in (c), expressed via transient transfection.

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