Table 2 Shared N-glycan alterations in non-invasive and invasive IPMNs as compared to the controls.
From: N-glycosylation in non-invasive and invasive intraductal papillary mucinous neoplasm
Relative abundance | (%) | p-value* | |||
|---|---|---|---|---|---|
Ctrl | Non-invasive | Invasive | Ctrl- Non-invasive | Ctrl-invasive | |
Neutral monosaccharide composition | |||||
H4N4 | 0.3 | 0.7 | 1.0 | 0.038 | 0.045 |
H6N3 | 0.5 | 1.1 | 1.3 | 0.038 | 0.015 |
H3N5F1 | 1.7 | 0.2 | 0.3 | 0.032 | 0.025 |
H8N2 | 13.9 | 9.3 | 8.2 | 0.032 | 0.015 |
Neutral N-glycan class | |||||
Monoantennary | 35.9 | 23.1 | 22.5 | 0.035 | 0.010 |
Acidic monosaccharide composition | |||||
H3N4P1 | 0.4 | 0.0 | 0.0 | 0.032 | 0.015 |
H5N3P1 | 2.7 | 0.2 | 0.0 | 0.032 | 0.015 |
H3N4F1P1 | 0.6 | 0.1 | 0.1 | 0.032 | 0.015 |
H6N3P1 | 7.4 | 1.5 | 0.8 | 0.038 | 0.015 |
H4N5F1P1 | 1.1 | 0.3 | 0.1 | 0.038 | 0.015 |
Acidic N-glycan class | |||||
Sialylated | 75.8 | 92.9 | 96.3 | 0.035 | 0.007 |
Monoantennary | 31.8 | 49.5 | 51.2 | 0.035 | 0.020 |
Sulfate/phosphate | 24.8 | 7.7 | 4.2 | 0.035 | 0.007 |
High-mannose type | 1.8 | 0.3 | 0.3 | 0.035 | 0.026 |
Pauci-mannose type | 1.0 | 0.2 | 0.1 | 0.035 | 0.012 |
Sulfate/phosphate in hybrid-type | 44.5 | 13.8 | 9.5 | 0.035 | 0.007 |
