Table 1 The 10 most upregulated and downregulated microRNAs in DLBCL patients vs. controls.

From: microRNA sequencing for biomarker detection in the diagnosis, classification and prognosis of Diffuse Large B Cell Lymphoma

MicroRNA

Base Mean

log2FoldChange

p-value

padj

hsa-miR-210-3p

842.9

3.51

2.33 × 10–29

1.45 × 10–26

hsa-miR-944

60.9

4.10

2.19 × 10–23

6.80 × 10–21

hsa-miR-12136

76.05

26.94

3.64 × 10–20

6.47 × 10–18

hsa-miR-3681-5p

75.3

5.16

3.33 × 10–20

6.47 × 10–18

hsa-miR-378i

24.9

3.01

3.01 × 10–17

4.16 × 10–15

hsa-miR-4454

183.4

2.35

1.01 × 10–16

1.04 × 10–14

hsa-miR-1291

354.7

4.02

1.84 × 10–16

1.76 × 10–14

hsa-miR-7974

111.8

3.46

1.87 × 10–15

1.45 × 10–13

hsa-miR-183-5p

891.1

3.40

5.77 × 10–15

3.59 × 10–13

hsa-miR-146a-5p

33,085.5

2.11

2.05 × 10–14

1.16 × 10–12

hsa-miR-215-5p

53.8

− 4.42

6.74 × 10–35

8.39 × 10–32

hsa-miR-150-5p

6310.7

− 3.22

3.46 × 10–25

1.44 × 10–22

hsa-miR-224-5p

47.7

− 3.30

5.11 × 10–21

1.27 × 10–18

hsa-miR-194-5p

37.8

− 4.33

6.19 × 10–17

7.00 × 10–15

hsa-miR-452-3p

7.2

− 2.33

2.10 × 10–16

1.87 × 10–14

hsa-miR-335-5p

127.6

− 2.74

6.20 × 10–16

5.14 × 10–14

hsa-miR-145-5p

2060.5

− 2.16

2.65 × 10–15

1.94 × 10–13

hsa-miR-139-5p

48.8

− 2.26

5.40 × 10–15

3.57 × 10–13

hsa-miR-497-5p

332.5

− 2.07

3.53 × 10–14

1.91 × 10–12

hsa-miR-10a-3p

10.2

− 2.29

7.45 × 10–12

2.73 × 10–10

  1. Positive Log2 Fold change represented the upregulation of microRNAs in DLBCL patients compared with healthy control individuals; Negative Log2 Fold change represented the downregulation of microRNAs in DLBCL patients compared with healthy control individuals; Base Mean: represented the average of the normalized count values, dividing by size factors, taken over all samples.
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