Figure 2 | Scientific Reports

Figure 2

From: Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains

Figure 2

ECOD groups statistics for over and underexpressed protein-coding genes in all cancer types. (A) ECOD statistics for overexpressed protein-coding genes. (B) ECOD statistics for underexpressed protein-coding genes. Blue bars (PDB) correspond to ECOD domains from experimentally identified structures. Orange bars (PDB&AF) correspond to ECOD and ECOD_AF domains from both experimentally and AlphaFold predicted structures. A-gr, ECOD architecture groups; X-gr, ECOD possible homology groups; H-gr, ECOD homology groups.

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