Figure 7 | Scientific Reports

Figure 7

From: Pan-cancer structurome reveals overrepresentation of beta sandwiches and underrepresentation of alpha helical domains

Figure 7

Representative domain structures from the largest A-groups. (A) Immunoglobulin-like beta sandwich domain of the cell surface interleukin-10 (PDB: 1Y6N). (B) Jelly-roll domain of the galectin GAL1 (PBD: 6M5Y). (C) AlphaFold model of ephrin type-A receptor 1 (P21709). (D) AlphaFold model of brefeldin A-inhibited guanine nucleotide-exchange protein 3 (Q5TH69). (E) EGF-like domain of Mucin-4 (AlphaFold: Q99102). Disulfide bonds are shown as sticks. (F) P-loop domains of Ras-related protein Rab-11A (PDB: 1OIV). Domain structures are colored in rainbow. (G) AlphaFold model of adhesion G-protein coupled receptor G1 (Q9Y653).

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