Figure 4

In vivo antitumor effect of RCQ combinations with different administration. (a) Flow chart of treatment intervention groups, (b) photographs of tumors in mice after dissection, (c) tumor volume, (d) tumor weight, and (e) tumor inhibition rate, (f) H&E staining of tumor tissue sections from four groups of mice. scale bar: 100 μm. (g) Body weight of mice. (h) The organ to body weight ratios of different groups of mice. (i) H&E staining of heart, liver, spleen, lung, and kidney. Neutrophil infiltration (yellow arrow), tumor metastasis (black arrow), and blood vessels were replaced by tumor cells (blue arrow), scale bar: 100 μm. Error bars represent mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 vs control.