Figure 2 | Scientific Reports

Figure 2

From: Correlates of estimated lifetime cruciate ligament survival inform potential rupture risk reduction strategies: findings from the Exceptional Aging in Rottweilers Study

Figure 2

Kaplan–Meier curves for lifetime cruciate ligament survival in the Exceptional Aging in Rottweilers Study (EARS) cohort (n = 123). Four curves show cruciate ligament survival stratified across four combinations of two risk variables (adult height, gonad exposure): SHORT–GONAD RETENTION (n = 51); SHORT–EED24months (n = 11); TALL–GONAD RETENTION (n = 39); TALL–EED24months (n = 22). EED24months = early endocrine disruption (EED) caused by gonad removal during the developmental period, i.e., the first 24 months of life. Hazard ratio (HR) and 95% confidence interval (95% CI) generated using Cox proportional hazard modelling using TALL-EED24months as reference (ref) group (HR = 1.0). In this survival analysis, time to event is time to first rupture, i.e., loss of any CCL survival. differs from reference group, p < .001. *differs from reference group, p = .02.

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