Figure 1

DNA methylation-based estimation of blood cell type composition in preterm infants. (A) Seven cell-type distributions in preterm infants with bronchopulmonary dysplasia (BPD) development or without (nonBPD) were estimated by DNA methylation profiles of cord blood and peripheral blood on postnatal days 14 and 28. Individual cell type data is in Additional file: Table S1. Mean ± S.E.M. presented. *p < 0.05 vs. time-matched nonBPD. (B) Blood cell type distribution of all preterm infants by gestational age quintile (Q). CD4T CD4 + T cells, CD8T CD8 + T cells, NK natural killer cells, Mono monocytes, Gran granulocytes, NRBC nucleated red blood cell. n = 107 in cord blood (93 nonBPD, 14 BPD). n = 93 on day 14 (81 nonBPD, 12 BPD). n = 82 on day 28 (71 nonBPD, 11 BPD).