Figure 2 | Scientific Reports

Figure 2

From: Prospective epigenome and transcriptome analyses of cord and peripheral blood from preterm infants at risk of bronchopulmonary dysplasia

Figure 2

Association between granulocytes, lymphocytes, and gestational age (GA) in preterm neonates diagnosed with bronchopulmonary dysplasia (BPD) or without (nonBPD). (A) Significant correlations between GA and peripheral blood granulocyte, or total lymphocyte, depicted by disease status and oxygen (O2) exposure days in neonatal intensive care unit (NICU). (B) Significantly elevated neutrophil (granulocyte)-lymphocyte ratio (NLR) in BPD compared to nonBPD in cord blood and peripheral blood on postnatal days 14 and 28. *, p < 0.05 vs. time-matched nonBPD. Individual data with mean ± S.E.M. presented. n = 107 in cord blood (93 nonBPD, 14 BPD). n = 93 in day 14 (81 nonBPD, 12 BPD). n = 82 in day 28 (71 nonBPD, 11 BPD). (C) Higher NLR was also associated with prolonged NICU O2 days and shorter GA on day 14 and  postnatal day 28 (Additional file 2: Fig. S1 A, B).

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