Table 2 Differentially expressed cord blood genes in bronchopulmonary dysplasia (BPD).

Immunity

BCL2

2.80E−03

− 1.90

BCL2 apoptosis regulator

CCR7

1.68E−02

− 1.83

C–C motif chemokine receptor 7

CD247

3.43E−02

− 1.54

CD247 molecule

CD27

5.80E−03

− 1.93

CD27 molecule

CD28

2.73E−02

− 1.63

CD28 molecule

CD79B

1.80E−02

− 1.95

CD79b molecule

HLA-DQA2†

1.82E−02

− 3.03

Major histocompatibility complex, class II, DQ alpha 2

ICOS

9.42E−03

− 1.81

Inducible T cell costimulator

IGLV2-14

1.24E−02

− 2.25

Immunoglobulin lambda variable 2–14

IL18R1*

3.61E−05

− 3.35

Interleukin 18 receptor 1

IL18RAP^†

4.08E−03

− 1.97

Interleukin 18 receptor accessory protein

IL21R

1.80E−02

− 2.34

Interleukin 1 receptor type 2

LCK^†

7.30E−03

− 1.83

LCK proto-oncogene, Src family tyrosine kinase

PGLYRP2

2.31E−02

8.32

Peptidoglycan recognition protein 2

RAG2

1.56E−02

8.96

Recombination activating 2

STAT4

5.13E−03

− 1.88

Signal transducer and activator of transcription 4

TRBJ1-1

1.52E−02

− 4.72

T cell receptor beta joining 1–1

TRAV16

7.99E−03

− 3.93

T cell receptor alpha variable 16

ZAP70

1.05E−02

− 1.93

Zeta chain of T cell receptor associated protein kinase 70

Immune-mediated inflammation, leukocyte migration, interferon signaling

CD83

7.56E−03

1.88

CD83 molecule

CXCL8

4.02E−02

3.96

C–X–C motif chemokine ligand 8

GBP3

6.74E−03

− 1.93

Guanylate binding protein 3

IFITM3^†

1.91E−02

− 1.90

Interferon induced transmembrane protein 3

ITGA6

3.32E−02

− 1.64

Integrin subunit alpha 6

MAPK9

3.59E−02

1.43

Mitogen-activated protein kinase 9

SELP^†

3.22E−02

− 2.21

Selectin P

SOCS1

1.23E−02

− 2.22

Suppressor of cytokine signaling 1

TLR4

1.13E−02

− 1.89

Toll like receptor 4

TNFSF8

6.95E−04

− 2.14

TNF superfamily member 8

Mitosis, chromosome segregation, DNA repair

AURKB

1.88E−02

1.85

Aurora kinase B

BORA*

3.71E−06

1.96

BORA aurora kinase A activator

CDCA8

3.11E−04

2.21

Cell division cycle associated 8

MKI67

1.06E−02

1.62

Marker of proliferation Ki-67

RAD51*

2.06E−05

3.00

RAD51 recombinase

SPC25^†

1.43E−02

2.76

SPC25 component of NDC80 kinetochore complex

TOP3A

5.76E−03

1.47

DNA topoisomerase III alpha

WEE1^†

2.86E−02

1.41

WEE1 G2 checkpoint kinase

Cell death, pyroptosis

CASP9

5.82E−03

1.53

Caspase 9

GSDMD

4.73E−02

− 1.49

Gasdermin D

GZMA^†

2.20E−03

− 1.87

Granzyme A

Respiratory disorders

AGER^†

2.55E−02

1.54

Advanced glycosylation end-product specific receptor

CAMP

7.17E−04

3.33

Cathelicidin antimicrobial peptide

HBG1*

1.43E−05

− 47.85

Hemoglobin subunit gamma 1

Growth, angiogenesis

ANGPT2^†

2.89E−02

5.46

Angiopoietin 2

B4GALT5*

4.15E−06

1.92

Beta-1,4-galactosyltransferase 5

GPS2

9.24E−03

− 1.88

G protein pathway suppressor 2

MMUT*

2.00E−05

1.67

Methylmalonyl-CoA mutase

PAPPA2*

5.09E−38

> 1000

Pappalysin 2

PGF^†

1.96E−02

5.60

Placental growth factor

SPOCK2^†

2.58E−02

− 1.91

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2

VEGFA

4.71E−03

2.01

Vascular endothelial growth factor A