Table 1 Study participants’ selected baseline characteristics before and after propensity score matching.

From: Hydrophilic and lipophilic statin use and risk of hearing loss in hyperlipidemia using a Common Data Model: multicenter cohort study

Characteristics

ANAM

Before matching

Standard

difference

After matching

Standard

difference

Hydrophilic users

(n = 5675)

Lipophilic users

(n = 8416)

Hydrophilic users

(n = 2510)

Lipophilic users

(n = 2510)

No. (%)

No. (%)

No. (%)

No. (%)

Age (years)

 40–44

316 (5.6)

426 (5.1)

0.02

148 (5.9)

141 (5.6)

0.01

 45–49

458 (8.1)

655 (7.8)

0.01

205 (8.2)

224 (8.9)

− 0.03

 50–54

786 (13.9)

1100 (13.1)

0.02

344 (13.7)

331 (13.2)

0.02

 55–59

974 (17.2)

1371 (16.3)

0.02

445 (17.7)

432 (17.2)

0.01

 60–64

986 (17.4)

1488 (17.7)

− 0.01

434 (17.3)

450 (17.9)

− 0.02

 65–69

856 (15.1)

1288 (15.3)

− 0.01

356 (14.2)

355 (14.1)

0.00

 70–74

669 (11.8)

1107 (13.2)

− 0.04

287 (11.4)

292 (11.6)

− 0.01

 75–79

527 (9.3)

861 (10.2)

− 0.03

241 (9.6)

251 (10)

− 0.01

 ≥ 80

102 (1.8)

120 (1.4)

0.03

50 (2)

34 (1.4)

0.05

Male

3107 (54.7)

3886 (46.2)

0.17

1222 (48.7)

1230 (49)

− 0.01

Female

2568 (45.3)

4530 (53.8)

− 0.17

1288 (51.3)

1280 (51)

0.01

Diabetes mellitus

1012 (17.8)

1865 (22.2)

− 0.11

494 (19.7)

458 (18.2)

0.04

Hypertensive disorder

2576 (45.4)

3458 (41.1)

0.09

1025 (40.8)

1076 (42.9)

− 0.04

Smoker

1013 (17.9)

1814 (21.6)

− 0.09

420 (16.7)

422 (16.8)

0.00

Characteristics

GURO

Before matching

Standard

Difference

After matching

Standard

difference

Hydrophilic users

(n = 4902)

Lipophilic users

(n = 7542)

Hydrophilic users

(n = 2182)

Lipophilic users

(n = 2182)

No. (%)

No. (%)

No. (%)

No. (%)

Age (years)

 40–44

279 (5.7)

388 (5.1)

0.02

127 (5.8)

131 (6)

− 0.01

 45–49

434 (8.9)

597 (7.9)

0.03

194 (8.9)

197 (9)

0.00

 50–54

676 (13.8)

1029 (13.6)

0.00

294 (13.5)

308 (14.1)

− 0.02

 55–59

883 (18)

1342 (17.8)

0.01

402 (18.4)

395 (18.1)

0.01

 60–64

952 (19.4)

1374 (18.2)

0.03

418 (19.2)

367 (16.8)

0.06

 65–69

719 (14.7)

1164 (15.4)

− 0.02

323 (14.8)

346 (15.9)

− 0.03

 70–74

517 (10.5)

934 (12.4)

− 0.06

246 (11.3)

246 (11.3)

0.00

 75–79

383 (7.8)

625 (8.3)

− 0.02

151 (6.9)

160 (7.3)

− 0.02

 ≥ 80

59 (1.2)

89 (1.2)

0.00

27 (1.2)

32 (1.5)

− 0.02

Male

2901 (59.2)

3553 (47.1)

0.24

1110 (50.9)

1162 (53.3)

− 0.05

Female

2001 (40.8)

3989 (52.9)

− 0.24

1072 (49.1)

1020 (46.7)

0.05

Diabetes mellitus

951 (19.4)

1790 (23.7)

− 0.11

456 (20.9)

432 (19.8)

0.03

Hypertensive disorder

2115 (43.1)

3520 (46.7)

− 0.07

938 (43)

887 (40.7)

0.05

Smoker

957 (19.5)

967 (12.8)

0.18

270 (12.4)

283 (13)

− 0.02

Characteristics

ANSAN

Before matching

Standard

Difference

After matching

Standard

Difference

Hydrophilic users

(n = 3174)

Lipophilic users

(n = 7673)

Hydrophilic users

(n = 1655)

Lipophilic users

(n = 1655)

No. (%)

No. (%)

No. (%)

No. (%)

Age (years)

 40–44

233 (7.3)

700 (9.1)

− 0.06

130 (7.9)

140 (8.5)

233 (7.3)

 45–49

404 (12.7)

975 (12.7)

0.00

210 (12.7)

177 (10.7)

404 (12.7)

 50–54

615 (19.4)

1313 (17.1)

0.06

312 (18.9)

310 (18.7)

615 (19.4)

 55–59

614 (19.3)

1397 (18.2)

0.03

271 (16.4)

292 (17.6)

614 (19.3)

 60–64

487 (15.3)

1142 (14.9)

0.01

249 (15)

265 (16)

487 (15.3)

 65–69

354 (11.2)

811 (10.6)

0.02

201 (12.1)

197 (11.9)

354 (11.2)

 70–74

258 (8.1)

674 (8.8)

− 0.02

155 (9.4)

146 (8.8)

258 (8.1)

 75–79

179 (5.6)

579 (7.5)

− 0.08

111 (6.7)

113 (6.8)

179 (5.6)

 ≥ 80

30 (0.9)

82 (1.1)

− 0.01

16 (1)

15 (0.9)

30 (0.9)

Male

1661 (52.3)

3951 (51.5)

0.02

815 (49.2)

814 (49.2)

1661 (52.3)

Female

1513 (47.7)

3722 (48.5)

− 0.02

840 (50.8)

841 (50.8)

1513 (47.7)

Diabetes mellitus

724 (22.8)

1661 (21.6)

0.03

446 (26.9)

461 (27.9)

724 (22.8)

Hypertensive disorder

1415 (44.6)

3177 (41.4)

0.06

771 (46.6)

800 (48.3)

1415 (44.6)

Smoker

419 (13.2)

1358 (17.7)

− 0.12

235 (14.2)

194 (11.7)

419 (13.2)