Table 2 Associations between longitudinal changes in time-varying BMI and trajectories of CRS and OPS.

From: Temporal relationships between BMI and obesity-related predictors of cardiometabolic and breast cancer risk in a longitudinal cohort

Outcome

Premenopausal (n = 197)

Postmenopausal (n = 203)

Intercept

Estimate (β, 95%CI)

P value

Intercept

Estimate (β, 95%CI)

P value

Model 1

 BMI → CRS

− 11.864

0.058 (0.009, 0.107)

0.020

− 17.440

0.045 (− 0.004, 0.095)

0.069

 BMI → OPS

23.968

1.021 (0.041, 1.995)

0.040

12.012

0.586 (0.249, 0.922)

 < 0.001

 CRS → OPS

− 13.154

0.784 (0.053, 1.512)

0.035

8.411

0.280 (0.029, 0.531)

0.029

 OPS → CRS

− 4.474

0.002 (− 0.000, 0.004)

0.115

− 4.179

0.005 (− 0.000, 0.011)

0.097

Model 2

 BMI → CRS

− 9.065

0.056 (0.006, 0.105)

0.028

− 18.798

0.049 (− 0.000, 0.099)

0.052

 BMI → OPS

27.774

0.918 (− 0.090, 1.921)

0.072

22.169

0.586 (0.243, 0.930)

0.001

 CRS → OPS

− 21.143

0.683 (− 0.065, 1.429)

0.073

15.826

0.306 (0.051, 0.561)

0.019

 OPS → CRS

− 0.987

0.002 (− 0.001, 0.004)

0.225

− 7.502

0.006 (− 0.000, 0.012)

0.070

Model 3

 BMI → CRS

− 7.614

0.057 (0.007, 0.107)

0.025

− 20.194

0.054 (0.004, 0.105)

0.033

 BMI → OPS

7.578

0.915 (− 0.090, 1.916)

0.073

14.293

0.588 (0.238, 0.939)

0.001

 CRS → OPS

− 47.354

0.690 (− 0.054, 1.433)

0.069

7.744

0.281 (0.022, 0.540)

0.034

 OPS → CRS

0.044

0.002 (− 0.001, 0.004)

0.225

− 9.425

0.005 (− 0.000, 0.011)

0.098

  1. Model 1 adjusted for age at baseline.
  2. Model 2 adjusted for age at baseline, education, career, smoking, and drinking.
  3. Model 3 adjusted for age at baseline, education, career, smoking, drinking, menarche age, and live birth.
  4. Significant values are in bold.
Back to article page