Figure 5

Effect of scES at L3 in a partial burst subgroup rat. The one transected animal having partial maintenance of burst activity at the chronic post-injury timepoint presented pre-scES with reduced compliance and some non-voiding contractions during the filling phase and large void volumes (A). scES at 150 μA for all frequencies triggered immediate and effective voids (B). The blue rectangles in A and B highlight the zoomed areas shown in (C and D). The phasic activity of EUS in SCI animals is characterized by irregular bursting pattern with an important reduction during the off periods. The scES at L3 level induced EUS activation (green arrows). However, the endogenous bursting activity (red arrows) remained active in this animal.