Figure 1
From: The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen
Stomal cell-specific ESR1 deletion in the Isl1-Esr1KO mice. ESR1 protein expression is evaluated by immunohistochemistry in control (A, B) and Isl1-Esr1KO (C, D) mice treated with OVX only (A, C) or E2 for three consecutive days (B, D), indicating successful deletion of Esr1 specifically in the stromal cells in the Isl1-Esr1KO mice. Scale bars, 100 μm.
