Table 1 the association of AREG and clinicopathological characteristicsa.

From: miR-33a-3p regulates METTL3-mediated AREG stability and alters EMT to inhibit pancreatic cancer invasion and metastasis

Characteristics

N of case

AREG level

P-value

Low

High

Total cases

36

18

18

 

Gender (n)

1.000

   Male

21

10

11

   Female

15

8

7

Age (year)

0.711

    ≤ 60

10

6

4

    > 60

26

12

14

TNM stage (AJCC)b

0.862

   I

16

9

7

   II

18

8

10

   III

2

1

1

T stage

0.045*

   T1

10

8

2

   T2

17

8

9

   T3

9

2

7

Pathological grade (n)

0.018*

   G1/G1 ~ G2/G2

27

10

17

   G2 ~ G3/G3

9

8

1

Lymph node metastasis (n)

0.733

   N0

22

10

12

   N1–N2

14

8

6

Nerve invasion (n)

1.000

   No

13

6

7

   Yes

23

12

11

Vascular invasion (n)

0.691

   No

28

13

15

   Yes

8

5

3

  1. Abbreviations: N of cases number of cases, TNM Tumor node metastasis, T stage Tumor stage.
  2. aFisher’s exact test or Chi-Square test, if appropriate, *P < 0.05.
  3. bAmerican Joint Committee on Cancer (AJCC), patients were staged in accordance with the 8th Edition of the AJCC Cancers’ TNM Classification.
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