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Figure 1

From: Author Correction: Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways

Figure 1

The effect of Flot-2 overexpression on the morphology of 6-10B cells. (A) The Flot-2 expression level in 5-8F, 6-10B and other NPC cells was detected by semi-quantitative RT-PCR and Western blotting. The expression of Flot-2 in 6-10B was weaker than that in other NPC cells. (B) Semi-quantitative RT-PCR and Western blotting were used to detect Flot-2 expression in 6-10B-Flot-2 cells. The 6-10B-Flot-2 cells achieved a comparable Flot-2 expression level to that in 5-8F cells. (C) The morphology of 6-10B and 6-10B-Flot-2 cells observed by inverted microscopy (200×). 6-10B-Flot-2 cells had a mesenchymal-like morphology with lamellipodia. (D) Cytoskeleton of 6-10B, 6-10B-Flot-2 cells and 5-8F cells were recorded under confocal laser-scanning microscope. 6-10B-Flot-2 cells exhibited a similar microfilament distribution pattern to 5-8F cells, consisting of a high-density distribution of microfilaments on the cell surface, which precedes the formation of conspicuous lamellipodia and membrane ruffles.

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