Figure 2 | Scientific Reports

Figure 2

From: Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction

Figure 2

Buried food test demonstrates olfactory impairment in Fmr1 KO male mice. (a) Left, WT male mice reached buried food pellet faster than KO mice (p = 0.0263; WT, black bars represent group mean ± standard error, each black circle represents one animal; KO, red bars represent group mean ± standard error, each red square represents one animal). Right, no difference in latency to uncover buried food pellet in female mice. (b) No difference in latency to retrieve unburied food pellet between KO and WT mice (left, male; right, female). (c) Left, WT males buried fewer marbles than KO male mice (p = 0.0135). Right, WT females buried fewer marbles than KO females (p = 0.0004). Statistical significance, indicated with * was determined with t-test followed by Tukey’s post hoc test.

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