Table 4 Comparison of parameters at the first Boolean remission and mean values of parameter thereafter between the G ≤ 6 and the G > 6.

From: The impact of time length to Boolean remission for tight disease activity control after acquisition in rheumatoid arthritis patients

 

At the first Boolean remission

After the first Boolean remission to last observation

G ≤ 6

G > 6

p-value

G ≤ 6

G > 6

p-value

MTX administration rate

70.3%

66.9%

0.47

77.5%

70.4%

0.10

Mean MTX dosage

7.9

8.8

< 0.05

8.2

8.3

0.84

GCS administration rate

29.4%

27.5%

0.67

29.6%

43.7%

0.24

Mean GCS dosage

3.2

3.3

0.86

3.3

3.9

0.30

b/tsDMARD administration rate

13.3%

27.5%

< 0.001

19.3%

20.4%

0.78

SDAI

1.03, 1.04

1.10, 1.00

0.49

2.91, 2.40

4.05, 3.03

< 0.001

SDAI remission rate

96.5%

96.5%

0.98

72.2%

58.0%

< 0.001

Boolean remission rate

100%

100%

1.00

62.0%

43.4%

< 0.001

HAQ-DI

0.370, 0.551

0.552, 0.600

< 0.01

0.364, 0.510

0.567, 0.599

< 0.001

PS-VAS

13.0, 18.4

20.7, 24.5

< 0.001

17.7, 14.9

24.1, 17.7

< 0.001

SHS

27.3, 49.8

70.7, 79.5

< 0.001

26.5, 48.6

69.0, 77.8

< 0.001

QOLS

0.845, 0.139

0.791, 0.156

0.79

0.828, 0.108

0.765, 0.128

< 0.001

  1. G ≤ 6, a patient group who achieved Boolean remission within 6 months from the baseline; G > 6, a patient group who achieved Boolean remission longer than 6 months from the baseline; MTX methotrexate, GCS glucocorticoid steroid, b/tsDMARD biologic or targeted synthetic disease-modifying anti-rheumatic drug, SDAI simplified disease activity index, HAQ-DI Health Assessment Questionnaire Disability Index, PS-VAS pain score using visual analog scale, SHS Sharp/van der Heijde Score, QOLS quality of life score.
  2. Units: time span, months; MTX dosage, mg per week; mean GCS dosage, mg per day; PS-VAS, millimeter. The other parameters' units are numerical values.
  3. In time span at the first Boolean remission columns, the time spans from the baseline to the first Boolean remission for each group are expressed.
  4. In time span after the first Boolean remission columns, the mean time spans from the first Boolean remission to the last observation for each group are expressed.
  5. In time span, SDAI, HAQ-DI, PS-VAS, and QOLS, mean values and standard deviations separated with comma are shown.
  6. In mean MTX dosage and mean GCS dosage, mean dosages in patients who was administered with each drug were shown.
  7. p-values in time span, mean MTX dosage, mean GCS dosage, SDAI, HAQ-DI, PS-VAS, SHS, and QOLS, are calculated using Mann–Whitney U-test. The other statistics are calculated using chi square test.
  8. Statistically significant columns are shown in bold style.
Back to article page