Figure 2 | Scientific Reports

Figure 2

From: Bovine milk-derived cells express transcriptome markers of pluripotency and secrete bioactive factors with regenerative and antimicrobial activity

Figure 2The alternative text for this image may have been generated using AI.

Single cell RNA sequencing (scRNA-seq) of milk-derived cells (MiDCs). (a) Uniform manifold approximation and projection plot of scRNA-seq data from MiDCs. Each dot represents one cell (i). Stacked violin plot showing the expression of common macrophage and mammary epithelial markers by subpopulation. The Y-axis represents the logarithmically normalized expression level of each gene in the dataset (ii). (b) Dot plot of macrophage clusters showing expression of known immune cell markers (i), of all epithelial clusters showing their expression of known mammary epithelial and fibroblast markers (ii), and off all 14 clusters showing their respective expression of known mammary stem and progenitor cell markers (iii). Circle size corresponds to percentage of cells expressing each marker (relative size showing percent expressed shown to the right of each plot with numbers representing percentages) and circle color represents the average expression of each marker on a log2 scale (color scheme for relative expression shown to the right of each plot ranging from light gray to dark blue).

Back to article page