Figure 6

Labile Cu²⁺ in Wilson’s disease patients before and after therapy. Labile Cu²⁺ (a) and total copper (b) concentrations in serum of a group of WD patients (N = 19) before and after medical therapy. Labile Cu²⁺ concentrations in serum were compared to total copper (c) and ceruloplasmin levels (d) before and after therapy. Correlation of total copper and ceruloplasmin concentrations in serum of patients before and after treatment (e). Data are presented as means + SD, and p values are indicated (unpaired t-test (a,b)) and as scatter plots, including Spearman correlation coefficients (r) and p-values (c–e).