Figure 4 | Scientific Reports

Figure 4

From: The influence of calcitriol and methylprednisolone on podocytes function in minimal change disease in vitro model

Figure 4

Analysis of selected cytokines release profile in the culture of podocytes treated with different concentrations of vitamin D3 or steroid. Different concentrations of vitamin D3 (D3; LOW = 100 nM, HIGH = 1000 nM) and methylprednisolone (MP; LOW = 40 μg/ml, HIGH = 200 μg/ml) were applied to podocytes in 48-h culture. Data presented as frequency of change relative to the LPS-PAN stimulation TNF-alpha, TGF-beta, IL-10, IL-6, IL-1beta, and IFN-gamma. Data are presented as a mean value with standard deviation (mean ± SD) (n = 10). The levels of significant differences were indicated with asterisks or exact p values: *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

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