Figure 2

Volcano plot of differential metabolites among groups. (A) Golmud hyperbilirubinemia (GeH) vs. healthy control. (B) Yushu hyperbilirubinemia (YsH) vs. healthy control. (C) GeH vs. YsH. (D) Hyperuricemia group vs. healthy control. Each point in the volcano plot represents a metabolite, the abscissa represents the logarithm of the quantitative difference between two samples of a metabolite, and the ordinate represents the VIP value. The green dots in the figure represent downregulated differentially expressed metabolites, the red dots represent upregulated differentially expressed metabolites, and the black dots represent metabolites that were detected but not significantly different.