Figure 2
From: Regulatory role of PI3K/Akt/WNK1 signal pathway in mouse model of bone cancer pain

Hematoxylin-eosin staining of tibia in mice. N: Normal group, BCP: Bone cancer pain group, Akt-i: GSK690693 group. N: Bone tissue and bone marrow cavity intact. BCP: The cancer cells engulfed the bone trabeculae and destroyed the bone cortex. Akt-i: The growth of cancer cells stagnated and the destruction of bone marrow cavity was not obvious.