Figure 1

Changes in the average fasting plasma glucose (A), total– (B), high-density lipoprotein– (C), low-density lipoprotein cholesterol (D), estimated glomerular filtration rate (E), body mass index (F) and glycosylated hemoglobin (HbA_1C; G) values of the two study cohorts during the observation period. Significant constant differences between the two cohorts could be justified in all parameters (A–F). Optimal fasting glucose, HBA_1C, total–, high-density lipoprotein–, and low-density lipoprotein cholesterol lipid values for T2DM patients are between 4.0 and 6.5 mmol/L, < 7.0%, < 4.0 mmol/L, > 1.0 mmol/L, < 2.0 mmol/L, respectively. Green and red colors represent colorectal cancer patients with and without type 2 diabetes mellitus, respectively. Thick lines and ribbons represent the predicted values and their 95% confidence intervals at the specific timepoints, respectively.