Table 4 Classification in each of the psychosocial, spinal tissue and nervous system from clusters derived within each of the sub-domains.

From: Towards data-driven biopsychosocial classification of non-specific chronic low back pain: a pilot study

Participant

Psychosocial classificationa

Spinal tissue classification

Nervous system classification

Overall classification

Domains contributing

Average 1-week pain intensity (0–100)

Oswestry Disability Index (0–100)

1

Normal psychosocial scores

Normal lumbar extension strength and T2

Low lumbar pressure-pain threshold only

Low lumbar pressure-pain threshold only

Nervous system

34

10

2

High psychosocial scores

Low lumbar extension strength and T2

High central sensitisation only

High psychosocial scores; Low lumbar extension strength and T2; High central sensitisation

Psychosocial; spinal tissue; nervous system

47

36

3

Normal psychosocial scores

Low lumbar extension strength and T2

Normal central sensitisation and lumbar pressure-pain threshold

Low lumbar extension strength and T2

Spinal tissue

10

22

4

High psychosocial scoress

Normal lumbar extension strength and T2

High central sensitisation and low lumbar pressure-pain threshold

High psychosocial scores; High central sensitisation and low lumbar pressure-pain threshold

Psychosocial; nervous system

33

16

5

High psychosocial scores

Low lumbar extension strength and T2

High central sensitisation and low lumbar pressure-pain threshold

High psychosocial scores; Low lumbar extension strength and T2; High central sensitisation and low lumbar pressure-pain threshold

Psychosocial; spinal tissue; nervous system

73

50

6

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation only

Nervous system

34

16

7

Normal psychosocial scores

Low lumbar extension strength and T2

High central sensitisation and low lumbar pressure-pain threshold

Low lumbar extension strength and T2; High central sensitisation and low lumbar pressure-pain threshold

Spinal tissue; nervous system

62

46

8

Normal psychosocial scores

Low lumbar extension strength and T2

Normal central sensitisation and lumbar pressure-pain threshold

Low lumbar extension strength and T2

Spinal tissue

16

16

9

Normal psychosocial scores

Low lumbar extension strength and T2

Low lumbar pressure-pain threshold only

Low lumbar extension strength and T2; Low lumbar pressure-pain threshold only

Spinal tissue; nervous system

39

22

10

High psychosocial scores

Low lumbar extension strength and T2

High central sensitisation only

High psychosocial scores; Low lumbar extension strength and T2; High central sensitisation

Psychosocial; spinal tissue; nervous system

54

32

11

Normal psychosocial scores

Low lumbar extension strength and T2

Normal central sensitisation and lumbar pressure-pain threshold

Low lumbar extension strength and T2

Spinal tissue

25

14

12

Normal psychosocial scores

Low lumbar extension strength and T2

High central sensitisation only

Low lumbar extension strength and T2; High central sensitisation

Spinal tissue; nervous system

51

30

13

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation only

Nervous system

57

20

14

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation only

Nervous system

12

6

15

Normal psychosocial scores

Low lumbar extension strength and T2

Normal central sensitisation and lumbar pressure-pain threshold

Low lumbar extension strength and T2

Spinal tissue

42

30

16

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation

Nervous system

11

14

17

High psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High psychosocial scores; High central sensitisation

Psychosocial; nervous system

53

22

18

Normal psychosocial scores

Normal lumbar extension strength and T2

Low lumbar pressure-pain threshold only

Low lumbar pressure-pain threshold

Nervous system

36

22

19

Normal psychosocial scores

Low lumbar extension strength and T2

High central sensitisation and low lumbar pressure-pain threshold

Low lumbar extension strength and T2; High central sensitisation and low lumbar pressure-pain threshold

Spinal tissue; Nervous system

45

18

20

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation only

Nervous system

22

18

21

Normal psychosocial scores

Normal lumbar extension strength and T2

High central sensitisation only

High central sensitisation only

Nervous system

50

20

  1. aHigh psychosocial symptoms include cognitive function, depressive symptoms, general self-efficacy, and symptoms of anxiety.