Table 2 Subscale and composite scores on the National Eye Institute Visual Function Questionnaire-25 for patients with ocular syphilis (n = 32 individuals) presented as mean ± standard deviation overall and for different clinical characteristics.

From: Vision-related quality of life in patients treated for ocular syphilis

Characteristic

Score

General health

General vision

Ocular pain

Near activities

Distance activities

Social functioning

Mental health

Role difficulties

Dependency

Driving

Color vision

Peripheral vision

Composite

Overall, n = 32 (100%)

66.7 ± 16.7

69.8 ± 20.0

84.8 ± 21.8

74.9 ± 23.1

75.2 ± 24.5

84.4 ± 24.9

60.9 ± 24.5

71.3 ± 29.3

82.8 ± 25.5

59.1 ± 39.6

89.1 ± 21.0

74.2 ± 27.3

75.5 ± 19.8

Gender, n (%)

 Woman, 8 (25%)

60.1 ± 18.2

72.5 ± 8.9

95.9 ± 26.3

71.8 ± 16.2

69.8 ± 20.3

81.2 ± 22.6

59.4 ± 27.8

75.0 ± 18.3

86.7 ± 16.2

56.7 ± 38.4

93.8 ± 17.7

75.0 ± 29.9

76.0 ± 15.9

 Man, 24 (75%)

68.8 ± 16.2

69.0 ± 22.6

84.4 ± 20.6

76.0 ± 25.2

77.0 ± 25.8

85.4 ± 26.0

61.5 ± 23.9

70.1 ± 32.4

81.5 ± 28.1

59.7 ± 40.9

87.5 ± 22.1

73.9 ± 27.1

75.3 ± 21.2

Age, n (%)

 ≤ 40 years, 11 (34%)

74.4 ± 16.1

78.2 ± 12.7

86.6 ± 12.3

93.4 ± 6.2

91.4 ± 10.9

98.6 ± 3.2

76.8 ± 14.0

95.0 ± 7.8

98.9 ± 2.4

89.2 ± 11.8

97.7 ± 7.5

95.5 ± 10.1

91.0 ± 6.3

 > 40 year, 21 (66%)

62.7 ± 15.9

65.5 ± 22.0

83.9 ± 24.2

65.4 ± 22.9

66.8 ± 25.5

77.1 ± 28.1

52.6 ± 24.9

58.9 ± 29.0

74.3 ± 28.1

35.9 ± 37.8

84.5 ± 24.3

63.1 ± 26.9

67.3 ± 19.6

HIV infection, n (%)

 Yes, 5 (15.6%)

69.0 ± 21.7

65.0 ± 23.7

72.5 ± 16.3

79.2 ± 25.8

73.4 ± 22.6

81.7 ± 24.6

65.0 ± 20.3

75.0 ± 36.7

75.0 ± 39.8

68.8 ± 46.4

90.0 ± 22.4

75.0 ± 30.6

74.5 ± 23.5

 No, 27 (84.4%)

66.3 ± 16.1

70.7 ± 19.6

87.0 ± 22.1

74.2 ± 23.0

75.6 ± 25.2

85.0 ± 25.4

60.2 ± 25.4

70.6 ± 28.6

84.3 ± 22.8

57.0 ± 39.1

88.9 ± 21.2

74.1 ± 27.3

75.6 ± 19.5

Bilateral involvement, n (%)

 Yes, 19 (59.4%)

62.1 ± 16.7

70.8 ± 18.2

78.8 ± 27.7

75.2 ± 21.8

76.9 ± 19.2

93.7 ± 7.7

63.1 ± 20.4

74.5 ± 22.7

85.5 ± 19.2

65.4 ± 35.2

88.5 ± 19.4

71.2 ± 22.5

77.1 ± 14.0

 No, 13 (40.6%)

69.9 ± 16.5

69.2 ± 21.6

88.8 ± 16.1

74.8 ± 24.5

74.1 ± 28.0

78.2 ± 20.4

59.5 ± 27.4

69.1 ± 22.8

80.9 ± 29.4

56.3 ± 42.1

89.5 ± 22.5

76.3 ± 30.6

74.4 ± 23.2

Classification of uveitisa, n (%)

 Posterior, 20 (62.5%)

68.6 ± 19.1

67.5 ± 22.5

84.4 ± 24.3

73.5 ± 25.5

76.0 ± 26.6

87.9 ± 23.3

66.0 ± 22.4

74.7 ± 29.4

81.6 ± 29.6

66.7 ± 39.8

93.8 ± 17.9

73.8 ± 27.5

76.9 ± 20.8

 Panuveitis, 11 (34.4%)

63.4 ± 12.8

76.4 ± 12.7

86.4 ± 18.1

79.9 ± 17.8

78.8 ± 14.0

84.8 ± 17.0

55.9 ± 24.8

69.3 ± 27.9

86.4 ± 17.6

53.1 ± 36.4

84.1 ± 23.1

79.6 ± 24.5

76.5 ± 14.8

Initial BCVA, n (%)

 > 20/50, 19 (59.4%)

67.5 ± 16.2

72.4 ± 16.5

82.9 ± 24.7

78.1 ± 19.9

83.1 ± 19.0

95.2 ± 6.9

70.3 ± 17.7

81.9 ± 20.6

91.8 ± 16.9

72.6 ± 34.5

92.1 ± 16.8

80.3 ± 24.4

81.9 ± 14.0

 ≤ 20/50, 13 (40.6%)

65.6 ± 18.1

66.1 ± 24.5

87.5 ± 16.9

70.4 ± 27.3

63.8 ± 27.6

68.6 ± 32.8

47.3 ± 27.2

55.7 ± 33.8

69.7 ± 30.6

37.9 ± 39.3

84.6 ± 26.1

65.4 ± 29.8

66.1 ± 23.5

Antibiotic treatment, n (%)

 IV penicillin G, 19 (59.5%)

66.4 ± 18.2

65.3 ± 23.2

83.6 ± 22.1

68.2 ± 26.5

69.0 ± 26.5

78.9 ± 29.4

57.4 ± 26.4

62.5 ± 33.2

77.3 ± 30.3

51.3 ± 44.1

85.5 ± 24.0

69.7 ± 30.7

70.3 ± 22.8

 IV ceftriaxone, 13 (40.6%)

67.2 ± 15.0

76.5 ± 12.0

86.5 ± 21.9

84.8 ± 12.1

84.3 ± 18.3

92.3 ± 13.8

66.2 ± 21.3

84.2 ± 16.3

90.9 ± 13.7

69.2 ± 32.2

94.2 ± 15.0

80.8 ± 20.8

82.9 ± 11.3

Corticosteroid treatment, n (%)

 Yes, 21 (65.6%)

68.0 ± 12.5

72.9 ± 15.1

88.1 ± 15.6

77.7 ± 19.8

79.0 ± 20.7

86.2 ± 24.1

61.9 ± 22.8

74.1 ± 26.1

89.6 ± 16.2

58.8 ± 39.5

91.7 ± 18.3

75.0 ± 26.2

78.0 ± 16.6

 No, 11 (34.4%)

64.4 ± 23.4

64.1 ± 27.0

78.4 ± 30.2

69.7 ± 28.6

68.0 ± 30.2

81.1 ± 27.4

59.1 ± 28.5

65.9 ± 35.4

69.8 ± 34.8

60.4 ± 45.8

84.1 ± 25.7

72.7 ± 30.5

70.6 ± 25.0

Final BCVA, n (%)

 > 20/50, 26 (81.3%)

68.2 ± 16.3

74.2 ± 15.3

85.1 ± 20.0

81.0 ± 18.9

82.2 ± 18.6

89.4 ± 17.7

67.7 ± 20.5

80.8 ± 21.6

89.7 ± 20.4

67.9 ± 34.3

93.3 ± 16.7

78.9 ± 24.2

81.2 ± 15.2

 ≤ 20/50, 6 (18.7%)

60.4 ± 18.9

50.8 ± 28.0

83.3 ± 30.3

48.6 ± 22.0

45.0 ± 25.0

62.5 ± 39.7

31.7 ± 18.9

30.0 ± 22.5

53.1 ± 25.5

0.0 ± 0.0

70.8 ± 29.2

54.1 ± 33.2

50.5 ± 18.7

  1. HIV human immunodeficiency virus, BCVA best-corrected visual acuity, IV intravenous.
  2. Statistical analyses were performed by Mann–Whitney U test, with bold values denoting statistical significance (p < 0.05).
  3. aIntermediate uveitis was not included as this group included one individual.