Figure 3

ANK3 mRNA moderates the relationship between sexual abuse and earlier age at onset of mania/hypomania. Process, moderation analysis. ß = − 1.23, p = .006. Adjusted for age, sex, medication, Daily Defined Dose, diagnosis (schizophrenia spectrum/bipolar disorders) and time of blood sample. High ANK3 group = 1 SD > mean levels. Intermediate ANK3 group = mean ANK3 levels, and Low ANK3 group = 1 SD < mean levels, AAO = age at onset.