Figure 3 | Scientific Reports

Figure 3

From: Metabolites for monitoring symptoms and predicting remission in patients with depression who received electroconvulsive therapy: a pilot study

Figure 3

Changes in plasma metabolites levels by the first ECT session in remission and non-remission groups. Plasma metabolites fluctuation by the first ECT session were assessed in the remission and the non-remission groups (A). PLS-DA score plot showing the change of levels of metabolites between T1 and T2 (B left). PLS-DA score plot also showed that the remission and the non-remission groups formed different clusters (B right). VIP scores for Fig. 3B were shown in Table S7. Volcano plot comparing the levels of metabolites between T1 and T2 in the remission group. The blue and red dots represent significantly (p < 0.05) downregulated and upregulated metabolites (C). The changes in levels of some metabolites levels significantly changed by the first ECT in the remission group, whereas not in the non-remission group (D). Abbreviations: ECT, electroconvulsive therapy; GABA, gamma-aminobutyric acid; γGlu-Glu, gamma glutamyl-glutamic acid. *p < 0.05, **p < 0.01.

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