Table 2 The APZ solubility at distinctive operational conditions (12–30 MPa) and (308–338 K).
From: Experimental solubility of aripiprazole in supercritical carbon dioxide and modeling
Temperature (K)a | Pressure (MPa)a | Density (kg.m−3)b | Y2 × 105 (Mole Fraction) | Standard deviation of the mean, SD(ȳ) × (105) | Expanded uncertainty × 106 | S × 10 (Solubility (g.l−1)) |
|---|---|---|---|---|---|---|
308 | 12 | 768.42 | 0.303 | 0.015 | 0.306 | 0.237 |
15 | 816.06 | 0.391 | 0.026 | 0.526 | 0.325 | |
18 | 848.87 | 0.467 | 0.022 | 0.450 | 0.404 | |
21 | 874.4 | 0.513 | 0.034 | 0.688 | 0.457 | |
24 | 895.54 | 0.569 | 0.050 | 1.007 | 0.520 | |
27 | 913.69 | 0.634 | 0.064 | 1.287 | 0.591 | |
30 | 929.68 | 0.679 | 0.079 | 1.586 | 0.644 | |
318 | 12 | 659.73 | 0.262 | 0.012 | 0.246 | 0.176 |
15 | 743.17 | 0.357 | 0.023 | 0.466 | 0.270 | |
18 | 790.18 | 0.471 | 0.031 | 0.627 | 0.379 | |
21 | 823.7 | 0.573 | 0.050 | 1.007 | 0.481 | |
24 | 850.1 | 0.675 | 0.079 | 1.586 | 0.585 | |
27 | 872.04 | 0.741 | 0.072 | 1.448 | 0.659 | |
30 | 890.92 | 0.801 | 0.090 | 1.807 | 0.727 | |
328 | 12 | 506.85 | 0.231 | 0.007 | 0.148 | 0.119 |
15 | 654.94 | 0.304 | 0.021 | 0.425 | 0.203 | |
18 | 724.13 | 0.496 | 0.025 | 0.510 | 0.366 | |
21 | 768.74 | 0.643 | 0.048 | 0.969 | 0.504 | |
24 | 801.92 | 0.759 | 0.073 | 1.468 | 0.620 | |
27 | 828.51 | 0.847 | 0.086 | 1.729 | 0.716 | |
30 | 850.83 | 0.913 | 0.077 | 1.551 | 0.792 | |
338 | 12 | 384.17 | 0.183 | 0.006 | 0.126 | 0.072 |
15 | 555.23 | 0.258 | 0.017 | 0.344 | 0.146 | |
18 | 651.18 | 0.499 | 0.043 | 0.866 | 0.331 | |
21 | 709.69 | 0.699 | 0.056 | 1.129 | 0.506 | |
24 | 751.17 | 0.877 | 0.078 | 1.570 | 0.671 | |
27 | 783.29 | 0.958 | 0.095 | 1.910 | 0.764 | |
30 | 809.58 | 1.036 | 0.120 | 2.409 | 0.855 |