Table 3 HLA types of patients with immune checkpoint inhibitor-associated uveitis.

From: HLA-DRB1*04:05 is involved in the development of Vogt–Koyanagi–Harada disease-like immune-related adverse events in patients receiving immune checkpoint inhibitors

Case

ICIU form

HLA-A

HLA-B

HLA-C

HLA-DRB1

HLA-DQB1

HLA-DRB345

Case 1

VKH-like

A*02

A*26

B*40

B*59

C*01

C*03

DRB1*04:05

DRB1*09:01

DQB1*03:03

DQB1*04:01

DRB4*01

DRB4*01

Case 2

Nonspecific

A*26

A*26

B*40

B*40

C*03

C*07

DRB1*12:01

DRB1*14:05

DQB1*03:01

DQB1*05:03

DRB3*01:01

DRB3*02:02

Case 4

Nonspecific

A*02

A*24

B*39

B*39

C*07

C*07

DRB1*08:03

DRB1*09:01

DQB1*03:03

DQB1*06:01

DRB4*01

Blank

Case 5

VKH-like

A*02

A*26

B*39

B*46

C*01

C*07

DRB1*04:05

DRB1*09:01

DQB1*03:03

DQB1*04:01

DRB4*01

DRB4*01

Case 7

Nonspecific

A*26

A*31

B*40

B*40

C*03

C*03

DRB1*08:03

DRB1*09:01

DQB1*03:03

DQB1*06:01

DRB4*01

Blank

Case 8

VKH-like

A*24

A*24

B*52

B*59

C*01

C*12

DRB1*04:05

DRB1*04:05

DQB1*04:01

DQB1*04:01

DRB4*01

DRB4*01

Case 9

VKH-like

A*02

A*26

B*15

B*54

C*01

C*03

DRB1*04:05

DRB1*12:01

DQB1*03:01

DQB1*04:01

DRB3*01:01

DRB4*01

  1. HLA typing was not performed for Cases 3 and 6.
  2. ICIU immune checkpoint inhibitor-associated uveitis, VKH-like Vogt–Koyanagi–Harada disease-like uveitis.
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