Figure 1 | Scientific Reports

Figure 1

From: Purinergic neurotransmission receptor P2X4 silencing alleviates intracerebral hemorrhage-induced neuroinflammation by blocking the NLRP1/Caspase-1 pathway

Figure 1

P2X4 is highly expressed in the brain tissues of ICH mice. (A) Hematoxylin–eosin (HE) staining of mouse brain tissues was performed in sham group, 6 h, 24 h, 72 h, and 7d-post ICH. Scale bar = 50 um (B) The number of surviving neuronal cells was quantified. (C) The mRNA level of P2X7 mouse ipsilateral hemispheres was detected by qRT-PCR at different time points. (D) The mRNA level of P2X4 mouse ipsilateral hemispheres was detected by qRT-PCR at different time points. One-Way ANOVA and Tukey’s multiple comparisons test was used. N = 6. ** P < 0.01 versus Sham.

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