Figure 7 | Scientific Reports

Figure 7

From: Purinergic neurotransmission receptor P2X4 silencing alleviates intracerebral hemorrhage-induced neuroinflammation by blocking the NLRP1/Caspase-1 pathway

Figure 7

The NLRP1/Caspase-1 pathway mediates the effects of P2X4 silencing on neurological function and inflammation. (A–C) The serum levels of IL-1β (A), IL-6 (B), and TNF-α (C) were detected with ELISA. One-Way ANOVA and Tukey’s multiple comparisons test was used. N = 6. ** P < 0.01 versus Sham, ## P < 0.01 versus ICH, and @@ P < 0.01 versus AAV-P2X4-1.

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