Table 1 Clinical characteristics associated with stroke recurrence (SR) after 90 days follow-up.

From: Lipidomic signature of stroke recurrence after transient ischemic attack

 

All N = 460

Non-SR N = 423 (92.0%)

SR N = 37 (8.0%)

p valuea

Age, mean (SD)

71.4 (13.6)

71.4 (13.6)

70.4 (14.3)

0.662

Female, n (%)

221 (48.0)

198 (46.8)

23 (62.2)

0.086

Previous ischemic stroke, n (%)

32 (7.0)

25 (5.9)

7 (18.9)

0.003

Hypertension, n (%)

327 (71.1)

303 (71.6)

24 (64.9)

0.384

IHD, n (%)

56 (12.2)

53 (12.5)

3 (8.1)

0.43

Atrial fibrillation

112 (24.3)

101 (23.9)

11 (29.7)

0.426

Diabetes mellitus, n (%)

122 (26.5)

111 (26.2)

11 (29.7)

0.645

Smoking, n (%)

25 (5.4)

24 (5.7)

1 (2.7)

0.445

Hypercholesterolemia, n (%)

224 (48.7)

208 (49.2)

16 (43.29

0.489

Cluster TIA, n (%)

90 (19.6)

80 (18.9)

10 (27.0)

0.233

Duration

   

0.09

  < 10’

86 (18.7)

84 (19.9)

2 (5.4)

 

 10’–60’

203 (44.1)

185 (43.7)

18 (48.6)

 

  > 60’, n (%)

171 (37.2)

154 (36.4)

17 (45.9)

 

Motor impairment, n (%)

245 (53.3)

218 (51.5)

27 (73.0)

0.012

ABCD2 groups

    

 0–3

116 (25.2)

110 (26.09

6 (16.2)

0.106

 4–5

252 (54.8)

233 (55.1)

19 (51.4)

 

 6–7

92 (20.09

80 (18.9)

12 (32.4)

 

DWI abnormality, n (%)

80 (36.7)

64 (32.7)

16 (72.7)

 < 0.001

Etiology, n(%)

    

 LAA

94 (20.4)

81 (19.1)

13 (35.1)

0.021

 CE

125 (27.2)

113 (29.1)

12 (32.4)

0.453

 SV

130 (28.3)

123 (29.1)

7 (18.9)

0.188

 Undetermined

104 (22.6)

100 (23.6)

4 (10.8)

0.099

Cholesterol total, mean (SD) mg/dL

180.2 (45.6)

180.8 (46.3)

174.5 (38.1)

0.509

LDL, mean (SD) mg/dL

111.1 (36.7)

111.4 (37.6)

107.2 (25.5)

0.639

HDL, mean (SD) mg/dL

47.4 (13.4)

47.2 (12.8)

48.9 (18.5)

0.578

Triglycerides, mean (SD) mg/dL

134.2 (86.8)

135.6 (89.0)

120.3 (61.4)

0.413

Previous statin treatment, n (%)

146 (33.7)

135 (34.0)

11 (30.6)

0.675

  1. Plus–minus values are means ± SD. Percentages may not total 100 because of rounding.
  2. Significant values are in italics.
  3. a: student t-test.
  4. SR Stroke recurrence; IHD Ischemic heart disease; TIA Transient ischemic attack; ABCD2 Age, blood pressure, clinical features, symptom duration, and diabetes mellitus risk scores; DWI Diffusion-weighted imaging; LAA Large-artery occlusive disease; CE Cardioembolism; SV Small vessel diseases; LDL Low-density lipoprotein; HDL High-density lipoprotein; TG Triglycerides.