Table 1 Summary of investigated PNA linkers. The linkers are composed of either double-stranded (ds) or single strand (ss) PNA architectures. Successful particle formation is indicated by ‘YES’ (observed) or ‘NO’ (not observed).
From: Peptide nucleic acid-zirconium coordination nanoparticles
PNA sequences | Description | Architecture | Particle formation |
|---|---|---|---|
GC-ACI | Palindromic | ds | NO |
GC-TPA | Palindromic | ds | NO |
CATG-ACI | Palindromic | ds | NO |
CATG-TPA | Palindromic | ds | NO |
GCATGC-ACI | Palindromic | ds | NO |
GCATGC-TPA | Palindromic | ds | YES |
CAGTACTG-ACI | Palindromic | ds | NO |
CAGTACTG-TPA | Palindromic | ds | YES |
CGTGAC-TPA + GTCACG-TPA | Non-palindromic | ds | YES |
CGTGAC-TPA + GTCACG | Non-palindromic | ds | minor formation |
PAMBA-CGTGAC-TPA + GTCACG | Non-palindromic | ds | YES |
PAMBA-CGTGAC-TPA | Non-palindromic | ss | YES |
PAMBA-GCAGCT-TPA | Non-palindromic | ss | YES |
PAMBA-CCTCTTACCTCAGTTACA-TPA | Non-palindromic (705 SSO) | ss | YES |
