Figure 1 | Scientific Reports

Figure 1

From: Cardamonin protects against iron overload induced arthritis by attenuating ROS production and NLRP3 inflammasome activation via the SIRT1/p38MAPK signaling pathway

Figure 1

CAR reduces the severity of KOA in the knee joint. (a) Representative graphs of Safranin-O/Fast Green staining (left), Prussian blue staining (middle), H&E staining (right) (Scale bar = 200 μm). (b) OARSI scores of Safranin O/ Prussian blue staining. (c) Iron deposition in the knee joint of mice. (d) Representative 3D images of the knee joint. Quantitative analysis of (e) BV/TV, Tb.Th, Tb. N, Tb.Sp. (Each group was compared with the MOD group. data are presented as standard deviation ± mean; # P < 0.0001, *** P < 0.001, ** P < 0.01, * P < 0.05 vs. Mod).

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