Figure 5 | Scientific Reports

Figure 5

From: Cardamonin protects against iron overload induced arthritis by attenuating ROS production and NLRP3 inflammasome activation via the SIRT1/p38MAPK signaling pathway

Figure 5

CAR inhibits MAPK signaling expression through activation of SIRT1. (a,b) Chondrocytes were treated with 100 μm FAC and co-cultured with 0, 2.5, and 5 μm CAR, and p38, p-p38, and SIRT1 protein levels were observed using protein blots, and statistical results are shown in bar graphs (data are presented as standard deviation ± mean; # P < 0.0001, *** P < 0.001, ** P < 0.01, * P < 0.05 vs. Mod).

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